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PIP5K1A mutations in 7 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Lung adenocarcinoma, Bladder carcinoma, Breast carcinoma, Lung squamous cell carcinoma, Renal clear cell carcinoma, Cutaneous melanoma, Stomach adenocarcinoma

PIP5K1A
Ensembl id ENSG00000143398
Mutated samples
Coding Sequence 40 (0.6%)
Protein Affecting 31 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PIP5K1A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma Yes 5 5 1.28
Cutaneous melanoma Yes 7 4 1.08
Breast carcinoma Yes 5 3 0.26
Lung squamous cell carcinoma Yes 3 3 1.72
Bladder carcinoma Yes 2 2 2.04
Renal clear cell carcinoma Yes 2 2 0.48
Stomach adenocarcinoma Yes 3 2 1.24
Head and neck squamous cell carcinoma No 4 4 1.07
Thyroid carcinoma No 1 1 0.31
Uterine corpus endometrioid carcinoma No 1 1 0.43
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence