Top
PIK3C2B is detected as a mutational cancer driver in 1 cancer type: Cutaneous melanoma

PIK3C2B
Ensembl id ENSG00000133056
Mutated samples
Coding Sequence 105 (1.5%)
Protein Affecting 80 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
CM C
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PIK3C2B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 30 17 4.61
Stomach adenocarcinoma No 9 8 4.97
Head and neck squamous cell carcinoma No 8 8 2.13
Breast carcinoma No 9 7 0.61
Lung squamous cell carcinoma No 8 7 4.02
Lung adenocarcinoma No 8 6 1.53
Non small cell lung carcinoma No 4 4 12.90
Colorectal adenocarcinoma No 4 4 1.75
Bladder carcinoma No 4 3 3.06
Renal clear cell carcinoma No 5 3 0.72
Small cell lung carcinoma No 3 3 4.35
Glioblastoma multiforme No 3 3 0.79
Prostate adenocarcinoma No 2 2 0.82
Neuroblastoma No 2 2 0.95
Uterine corpus endometrioid carcinoma No 2 2 0.87
Esophageal carcinoma No 1 1 0.68
Chronic lymphocytic leukemia No 2 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence