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PIGG has not been detected as a mutational cancer driver

PIGG
Ensembl id ENSG00000174227
Mutated samples
Coding Sequence 73 (1.1%)
Protein Affecting 43 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PIGG gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 11 2.98
Bladder carcinoma No 6 6 6.12
Lung adenocarcinoma No 6 5 1.28
Lung squamous cell carcinoma No 6 4 2.30
Stomach adenocarcinoma No 6 4 2.48
Breast carcinoma No 2 2 0.17
Renal clear cell carcinoma No 4 2 0.48
Serous ovarian adenocarcinoma No 3 2 0.63
Head and neck squamous cell carcinoma No 4 2 0.53
Esophageal carcinoma No 2 2 1.37
Uterine corpus endometrioid carcinoma No 2 1 0.43
Multiple myeloma No 2 1 1.45
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Lower grade glioma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence