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PHKA1 has not been detected as a mutational cancer driver

PHKA1
Ensembl id ENSG00000067177
Mutated samples
Coding Sequence 84 (1.2%)
Protein Affecting 70 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PHKA1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 27 24 6.50
Lung squamous cell carcinoma No 6 6 3.45
Small cell lung carcinoma No 6 6 8.70
Breast carcinoma No 8 5 0.44
Lung adenocarcinoma No 5 4 1.02
Stomach adenocarcinoma No 5 4 2.48
Bladder carcinoma No 3 3 3.06
Uterine corpus endometrioid carcinoma No 4 3 1.30
Non small cell lung carcinoma No 3 3 9.68
Serous ovarian adenocarcinoma No 3 3 0.95
Renal clear cell carcinoma No 2 2 0.48
Head and neck squamous cell carcinoma No 3 2 0.53
Glioblastoma multiforme No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Neuroblastoma No 2 1 0.48
Colorectal adenocarcinoma No 1 1 0.44
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence