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PGAM4 has not been detected as a mutational cancer driver

PGAM4
Ensembl id ENSG00000226784
Mutated samples
Coding Sequence 21 (0.3%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PGAM4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma No 3 3 1.86
Lung adenocarcinoma No 2 2 0.51
Small cell lung carcinoma No 2 2 2.90
Esophageal carcinoma No 2 2 1.37
Breast carcinoma No 1 1 0.09
Lung squamous cell carcinoma No 2 1 0.57
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 2 1 0.43
Head and neck squamous cell carcinoma No 2 1 0.27
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Cutaneous melanoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence