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PEX5L has not been detected as a mutational cancer driver

PEX5L
Ensembl id ENSG00000114757
Mutated samples
Coding Sequence 73 (1.1%)
Protein Affecting 54 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PEX5L gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 11 2.98
Lung adenocarcinoma No 9 9 2.30
Lung squamous cell carcinoma No 10 7 4.02
Head and neck squamous cell carcinoma No 7 7 1.87
Serous ovarian adenocarcinoma No 3 3 0.95
Stomach adenocarcinoma No 3 3 1.86
Breast carcinoma No 3 2 0.17
Uterine corpus endometrioid carcinoma No 3 2 0.87
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Glioblastoma multiforme No 2 2 0.53
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 2 1 1.02
Renal clear cell carcinoma No 1 1 0.24
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence