Top
IntOGen
PDGFRA × Lung Squamous Cell Carcinoma ×

PDGFRA is detected as a mutational cancer driver in Lung Squamous Cell Carcinoma

PDGFRA reports in Lung Squamous Cell Carcinoma (LUSC)

Cancer type details
Lung Squamous Cell Carcinoma
Cohorts 6
Samples 703
Mutations 4,282,647
Driver genes 75
Gene details
PDGFRA
Ensembl ID ENSG00000134853
Transcript ID ENST00000257290
Protein ID ENSP00000257290
Cohorts where is driver 2
Mutated samples 8
Mutated samples (%) 1.14
Mutations 35
Mode of action Loss of function
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence