IntOGen - PDGFRA gene cancer mutations

PDGFRA is detected as a mutational cancer driver

PDGFRA reports

Methods
Mutation distribution

Gene details

PDGFRA
Ensembl ID ENSG00000134853 Transcript ID ENST00000257290 Protein ID ENSP00000257290
Cancer types where is driver 6 Cohorts where is driver 9 Mutated samples 43 Mutations 675
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence