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PDE4DIP has not been detected as a mutational cancer driver

PDE4DIP
Ensembl id ENSG00000178104
Mutated samples
Coding Sequence 84 (1.2%)
Protein Affecting 42 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PDE4DIP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 40 21 5.69
Small cell lung carcinoma No 5 5 7.25
Esophageal carcinoma No 10 5 3.42
Breast carcinoma No 5 3 0.26
Neuroblastoma No 3 3 1.43
Head and neck squamous cell carcinoma No 4 2 0.53
Prostate adenocarcinoma No 4 1 0.41
Medulloblastoma No 2 1 0.48
Multiple myeloma No 2 1 1.45
Hepatocarcinoma No 3 0 0.00
Non small cell lung carcinoma No 5 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence