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PCYT1A has not been detected as a mutational cancer driver

PCYT1A
Ensembl id ENSG00000161217
Mutated samples
Coding Sequence 84 (1.2%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PCYT1A gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 27 8 2.17
Stomach adenocarcinoma No 10 5 3.11
Colorectal adenocarcinoma No 6 3 1.31
Breast carcinoma No 5 2 0.17
Uterine corpus endometrioid carcinoma No 6 2 0.87
Glioblastoma multiforme No 3 2 0.53
Lung adenocarcinoma No 5 1 0.26
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 3 1 0.27
Esophageal carcinoma No 1 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 2 0 0.00
Acute myeloid leukemia No 1 0 0.00
Lung squamous cell carcinoma No 3 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Serous ovarian adenocarcinoma No 5 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence