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PARP4 is detected as a mutational cancer driver

PARP4 reports

Gene details
PARP4
Ensembl ID ENSG00000102699
Transcript ID ENST00000381989
Protein ID ENSP00000371419
Cancer types where is driver 3
Cohorts where is driver 3
Mutated samples 34
Mutations 582
Mode of action Activating
Known driver False
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence