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PAPOLG has not been detected as a mutational cancer driver

PAPOLG
Ensembl id ENSG00000115421
Mutated samples
Coding Sequence 41 (0.6%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all PAPOLG gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 6 5 1.28
Cutaneous melanoma No 9 5 1.36
Renal clear cell carcinoma No 5 4 0.96
Uterine corpus endometrioid carcinoma No 4 3 1.30
Stomach adenocarcinoma No 5 3 1.86
Lung squamous cell carcinoma No 2 2 1.15
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 2 1 0.09
Thyroid carcinoma No 1 1 0.31
Serous ovarian adenocarcinoma No 1 1 0.32
Head and neck squamous cell carcinoma No 1 1 0.27
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence