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OSBPL6 has not been detected as a mutational cancer driver

OSBPL6
Ensembl id ENSG00000079156
Mutated samples
Coding Sequence 83 (1.2%)
Protein Affecting 65 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all OSBPL6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 19 5.15
Lung adenocarcinoma No 7 7 1.79
Lung squamous cell carcinoma No 9 6 3.45
Uterine corpus endometrioid carcinoma No 6 5 2.17
Stomach adenocarcinoma No 8 5 3.11
Head and neck squamous cell carcinoma No 6 5 1.33
Esophageal carcinoma No 5 5 3.42
Breast carcinoma No 4 4 0.35
Colorectal adenocarcinoma No 4 4 1.75
Renal clear cell carcinoma No 3 1 0.24
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 2 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence