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ORC4 has not been detected as a mutational cancer driver

ORC4
Ensembl id ENSG00000115947
Mutated samples
Coding Sequence 22 (0.3%)
Protein Affecting 13 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ORC4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 4 4 1.08
Renal clear cell carcinoma No 3 3 0.72
Lung adenocarcinoma No 2 2 0.51
Stomach adenocarcinoma No 3 2 1.24
Breast carcinoma No 1 1 0.09
Serous ovarian adenocarcinoma No 2 1 0.32
Hepatocarcinoma No 3 0 0.00
Bladder carcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence