OR2T8 has not been detected as a mutational cancer driver

Ensembl id ENSG00000177462
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 35 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all OR2T8 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 11 9 2.30
Lung squamous cell carcinoma No 8 8 4.60
Cutaneous melanoma No 17 8 2.17
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Breast carcinoma No 1 1 0.09
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Head and neck squamous cell carcinoma No 2 1 0.27
Esophageal carcinoma No 1 1 0.68
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence