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OR2L3 has not been detected as a mutational cancer driver

OR2L3
Ensembl id ENSG00000198128
Mutated samples
Coding Sequence 83 (1.2%)
Protein Affecting 64 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all OR2L3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 27 23 6.23
Lung adenocarcinoma No 15 15 3.84
Head and neck squamous cell carcinoma No 9 6 1.60
Stomach adenocarcinoma No 8 4 2.48
Breast carcinoma No 3 3 0.26
Lung squamous cell carcinoma No 6 3 1.72
Bladder carcinoma No 3 2 2.04
Hepatocarcinoma No 1 1 1.11
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 2 1 0.43
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 3 1 0.26
Esophageal carcinoma No 1 1 0.68
Non small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence