Top
OBSCN has not been detected as a mutational cancer driver

OBSCN
Ensembl id ENSG00000154358
Mutated samples
Coding Sequence 412 (6.1%)
Protein Affecting 289 (4.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all OBSCN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 112 73 19.78
Lung adenocarcinoma No 40 30 7.67
Breast carcinoma No 40 27 2.35
Uterine corpus endometrioid carcinoma No 27 24 10.43
Lung squamous cell carcinoma No 24 18 10.34
Glioblastoma multiforme No 23 16 4.22
Colorectal adenocarcinoma No 14 14 6.11
Head and neck squamous cell carcinoma No 19 14 3.73
Stomach adenocarcinoma No 28 13 8.07
Esophageal carcinoma No 12 10 6.85
Prostate adenocarcinoma No 13 9 3.70
Lower grade glioma No 7 7 4.14
Bladder carcinoma No 10 5 5.10
Serous ovarian adenocarcinoma No 7 5 1.58
Small cell lung carcinoma No 5 5 7.25
Pancreas adenocarcinoma No 3 3 1.40
Renal clear cell carcinoma No 5 3 0.72
Thyroid carcinoma No 5 3 0.93
Neuroblastoma No 3 3 1.43
Multiple myeloma No 3 2 2.90
Diffuse B cell lymphoma No 2 2 8.70
Acute lymphocytic leukemia No 2 2 1.64
Hepatocarcinoma No 3 1 1.11
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence