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NVL has not been detected as a mutational cancer driver

NVL
Ensembl id ENSG00000143748
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 34 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NVL gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 7 1.90
Breast carcinoma No 5 5 0.44
Lung adenocarcinoma No 4 4 1.02
Uterine corpus endometrioid carcinoma No 5 4 1.74
Lung squamous cell carcinoma No 4 3 1.72
Stomach adenocarcinoma No 6 3 1.86
Bladder carcinoma No 2 2 2.04
Colorectal adenocarcinoma No 4 2 0.87
Esophageal carcinoma No 2 2 1.37
Renal clear cell carcinoma No 1 1 0.24
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence