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NSUN3 has not been detected as a mutational cancer driver

NSUN3
Ensembl id ENSG00000178694
Mutated samples
Coding Sequence 41 (0.6%)
Protein Affecting 17 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NSUN3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 4 3 0.26
Lung squamous cell carcinoma No 4 3 1.72
Lung adenocarcinoma No 4 2 0.51
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 1 1 1.02
Cutaneous melanoma No 10 1 0.27
Uterine corpus endometrioid carcinoma No 2 1 0.43
Stomach adenocarcinoma No 3 1 0.62
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 3 1 0.27
Glioblastoma multiforme No 1 1 0.26
Hepatocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence