NRAS is detected as a mutational cancer driver in Acute Lymphoblastic Leukemia
NRAS reports in Acute Lymphoblastic Leukemia (ALL)
Cancer type details
Acute Lymphoblastic Leukemia |
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Cohorts
5
Samples 363 Mutations 202,546 Driver genes 28 |
Gene details
NRAS |
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Ensembl ID
ENSG00000213281
Transcript ID ENST00000369535 Protein ID ENSP00000358548 |
Cohorts where is driver
1
Mutated samples 31 Mutated samples (%) 8.54 Mutations 32 |
Mode of action Activating |
Known driver True |
Method signals per Cohort
Cohort | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
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ALL (Acute Lymphoblastic Leukemia) | 1692 | 48 | 2.84 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Samples (%) | Consequence | Driver | Driver score |
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