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NPRL2 has not been detected as a mutational cancer driver

NPRL2
Ensembl id ENSG00000114388
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 15 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NPRL2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Uterine corpus endometrioid carcinoma No 6 3 1.30
Lung adenocarcinoma No 5 2 0.51
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 3 2 0.53
Breast carcinoma No 6 1 0.09
Renal clear cell carcinoma No 4 1 0.24
Thyroid carcinoma No 1 1 0.31
Cutaneous melanoma No 10 1 0.27
Pylocytic astrocytoma No 1 1 0.99
Stomach adenocarcinoma No 2 1 0.62
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence