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NOTCH2 is detected as a mutational cancer driver

NOTCH2 reports

Gene details
NOTCH2
Ensembl ID ENSG00000134250
Transcript ID ENST00000256646
Protein ID ENSP00000256646
Cancer types where is driver 15
Cohorts where is driver 21
Mutated samples 171
Mutations 957
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence