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NOSTRIN has not been detected as a mutational cancer driver

NOSTRIN
Ensembl id ENSG00000163072
Mutated samples
Coding Sequence 39 (0.6%)
Protein Affecting 23 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NOSTRIN gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 7 1.90
Stomach adenocarcinoma No 6 4 2.48
Chronic lymphocytic leukemia No 2 2 0.69
Lung adenocarcinoma No 1 1 0.26
Bladder carcinoma No 2 1 1.02
Breast carcinoma No 1 1 0.09
Lung squamous cell carcinoma No 1 1 0.57
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 3 1 0.43
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 3 1 0.27
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 2 0 0.00
Multiple myeloma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence