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NMNAT2 has not been detected as a mutational cancer driver

NMNAT2
Ensembl id ENSG00000157064
Mutated samples
Coding Sequence 25 (0.4%)
Protein Affecting 16 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NMNAT2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 6 4 1.08
Lung adenocarcinoma No 3 3 0.77
Lung squamous cell carcinoma No 2 2 1.15
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 2 1 0.09
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 3 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 2 1 0.27
Hepatocarcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence