NLGN4Y has not been detected as a mutational cancer driver

Ensembl id ENSG00000165246
Mutated samples
Coding Sequence 39 (0.6%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NLGN4Y gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 15 11 2.98
Lung adenocarcinoma No 5 3 0.77
Lung squamous cell carcinoma No 3 3 1.72
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 3 2 0.53
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 1 1 3.23
Multiple myeloma No 1 1 1.45
Stomach adenocarcinoma No 1 1 0.62
Glioblastoma multiforme No 1 1 0.26
Neuroblastoma No 2 0 0.00
Chronic lymphocytic leukemia No 3 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence