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NHEJ1 has not been detected as a mutational cancer driver

NHEJ1
Ensembl id ENSG00000187736
Mutated samples
Coding Sequence 20 (0.3%)
Protein Affecting 6 (0.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NHEJ1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 3 1 0.26
Bladder carcinoma No 1 1 1.02
Breast carcinoma No 1 1 0.09
Renal clear cell carcinoma No 1 1 0.24
Stomach adenocarcinoma No 2 1 0.62
Colorectal adenocarcinoma No 2 1 0.44
Cutaneous melanoma No 4 0 0.00
Neuroblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence