IntOGen - NFKBIA gene cancer mutations

NFKBIA is detected as a mutational cancer driver

NFKBIA reports

Methods
Mutation distribution

Gene details

NFKBIA
Ensembl ID ENSG00000100906 Transcript ID ENST00000216797 Protein ID ENSP00000216797
Cancer types where is driver 3 Cohorts where is driver 4 Mutated samples 30 Mutations 192
Mode of action Loss of function
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence