IntOGen - NFKB2 gene cancer mutations

NFKB2 is detected as a mutational cancer driver

NFKB2 reports

Methods
Mutation distribution

Gene details

NFKB2
Ensembl ID ENSG00000077150 Transcript ID ENST00000369966 Protein ID ENSP00000358983
Cancer types where is driver 4 Cohorts where is driver 4 Mutated samples 32 Mutations 263
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence