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NFE2L2 × Non-Small Cell Lung Cancer ×

NFE2L2 is detected as a mutational cancer driver in Non-Small Cell Lung Cancer

NFE2L2 reports in Non-Small Cell Lung Cancer (NSCLC)

Cancer type details
Non-Small Cell Lung Cancer
Cohorts 2
Samples 564
Mutations 22,065,649
Driver genes 48
Gene details
NFE2L2
Ensembl ID ENSG00000116044
Transcript ID ENST00000397062
Protein ID ENSP00000380252
Cohorts where is driver 1
Mutated samples 16
Mutated samples (%) 2.84
Mutations 21
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence