NFE2L2 is detected as a mutational cancer driver
NFE2L2 reports
Gene details
NFE2L2 |
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Ensembl ID
ENSG00000116044
Transcript ID ENST00000397062 Protein ID ENSP00000380252 |
Cancer types where is driver
9
Cohorts where is driver 19 Mutated samples 302 Mutations 538 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BLCA (Bladder Urothelial Carcinoma) | 5436 | 829 | 15.25 |
ESCA (Esophageal Adenocarcinoma) | 5436 | 140 | 2.58 |
HC (Hepatocellular Carcinoma) | 5436 | 520 | 9.57 |
HNSC (Head and Neck Squamous Cell Carcinoma) | 5436 | 841 | 15.47 |
LUSC (Lung Squamous Cell Carcinoma) | 5436 | 104 | 1.91 |
UCEC (Endometrial Carcinoma) | 5436 | 592 | 10.89 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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