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NF1 × Lung Squamous Cell Carcinoma ×

NF1 is detected as a mutational cancer driver in Lung Squamous Cell Carcinoma

NF1 reports in Lung Squamous Cell Carcinoma (LUSC)

Cancer type details
Lung Squamous Cell Carcinoma
Cohorts 6
Samples 703
Mutations 4,282,647
Driver genes 75
Gene details
NF1
Ensembl ID ENSG00000196712
Transcript ID ENST00000358273
Protein ID ENSP00000351015
Cohorts where is driver 3
Mutated samples 58
Mutated samples (%) 8.25
Mutations 77
Mode of action Ambiguous
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence