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NCF2 mutations in 6 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Bladder carcinoma, Lung squamous cell carcinoma, Cutaneous melanoma, Uterine corpus endometrioid carcinoma, Head and neck squamous cell carcinoma, Glioblastoma multiforme

NCF2
Ensembl id ENSG00000116701
Mutated samples
Coding Sequence 65 (1.0%)
Protein Affecting 46 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NCF2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 14 9 2.44
Head and neck squamous cell carcinoma Yes 7 5 1.33
Bladder carcinoma Yes 4 3 3.06
Lung squamous cell carcinoma Yes 6 3 1.72
Uterine corpus endometrioid carcinoma Yes 3 3 1.30
Glioblastoma multiforme Yes 3 3 0.79
Breast carcinoma No 7 6 0.52
Serous ovarian adenocarcinoma No 4 4 1.27
Prostate adenocarcinoma No 3 3 1.23
Medulloblastoma No 2 2 0.95
Lung adenocarcinoma No 1 1 0.26
Renal clear cell carcinoma No 1 1 0.24
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 2 1 0.62
Colorectal adenocarcinoma No 2 1 0.44
Pancreas adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence