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NBPF10 has not been detected as a mutational cancer driver

NBPF10
Ensembl id ENSG00000163386
Mutated samples
Coding Sequence 184 (2.7%)
Protein Affecting 99 (1.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all NBPF10 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 47 28 7.59
Head and neck squamous cell carcinoma No 40 18 4.80
Prostate adenocarcinoma No 27 13 5.35
Glioblastoma multiforme No 16 10 2.64
Lower grade glioma No 19 6 3.55
Lung adenocarcinoma No 7 5 1.28
Bladder carcinoma No 9 5 5.10
Breast carcinoma No 6 4 0.35
Thyroid carcinoma No 4 4 1.24
Renal clear cell carcinoma No 4 2 0.48
Neuroblastoma No 2 2 0.95
Lung squamous cell carcinoma No 1 1 0.57
Serous ovarian adenocarcinoma No 1 1 0.32
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence