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N4BP2 has not been detected as a mutational cancer driver

N4BP2
Ensembl id ENSG00000078177
Mutated samples
Coding Sequence 90 (1.3%)
Protein Affecting 76 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all N4BP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 18 4.88
Breast carcinoma No 12 11 0.96
Head and neck squamous cell carcinoma No 6 6 1.60
Lung adenocarcinoma No 6 5 1.28
Bladder carcinoma No 6 5 5.10
Stomach adenocarcinoma No 5 5 3.11
Lung squamous cell carcinoma No 6 4 2.30
Uterine corpus endometrioid carcinoma No 6 4 1.74
Glioblastoma multiforme No 4 4 1.06
Hepatocarcinoma No 3 2 2.22
Multiple myeloma No 2 2 2.90
Small cell lung carcinoma No 2 2 2.90
Esophageal carcinoma No 3 2 1.37
Medulloblastoma No 1 1 0.48
Renal clear cell carcinoma No 2 1 0.24
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence