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MYO7B has not been detected as a mutational cancer driver

MYO7B
Ensembl id ENSG00000169994
Mutated samples
Coding Sequence 158 (2.3%)
Protein Affecting 103 (1.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MYO7B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 44 31 8.40
Lung adenocarcinoma No 27 16 4.09
Breast carcinoma No 12 10 0.87
Lung squamous cell carcinoma No 12 8 4.60
Head and neck squamous cell carcinoma No 11 8 2.13
Uterine corpus endometrioid carcinoma No 15 6 2.61
Serous ovarian adenocarcinoma No 4 4 1.27
Stomach adenocarcinoma No 7 4 2.48
Bladder carcinoma No 4 3 3.06
Glioblastoma multiforme No 4 3 0.79
Pancreas adenocarcinoma No 2 2 0.93
Esophageal carcinoma No 3 2 1.37
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 1 1 1.11
Renal clear cell carcinoma No 2 1 0.24
Neuroblastoma No 1 1 0.48
Lower grade glioma No 2 1 0.59
Colorectal adenocarcinoma No 2 1 0.44
Chronic lymphocytic leukemia No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence