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MYO1B has not been detected as a mutational cancer driver

MYO1B
Ensembl id ENSG00000128641
Mutated samples
Coding Sequence 74 (1.1%)
Protein Affecting 55 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MYO1B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Glioblastoma multiforme No 12 11 2.90
Cutaneous melanoma No 14 8 2.17
Lung adenocarcinoma No 7 6 1.53
Uterine corpus endometrioid carcinoma No 7 6 2.61
Colorectal adenocarcinoma No 5 4 1.75
Renal clear cell carcinoma No 3 3 0.72
Stomach adenocarcinoma No 5 3 1.86
Bladder carcinoma No 2 2 2.04
Breast carcinoma No 3 2 0.17
Esophageal carcinoma No 2 2 1.37
Hepatocarcinoma No 1 1 1.11
Lung squamous cell carcinoma No 3 1 0.57
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 3 1 0.34
Multiple myeloma No 3 1 1.45
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 1 1 0.32
Head and neck squamous cell carcinoma No 1 1 0.27
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence