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MYH15 has not been detected as a mutational cancer driver

MYH15
Ensembl id ENSG00000144821
Mutated samples
Coding Sequence 186 (2.7%)
Protein Affecting 137 (2.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MYH15 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 73 50 13.55
Lung squamous cell carcinoma No 18 16 9.20
Lung adenocarcinoma No 17 13 3.32
Small cell lung carcinoma No 8 8 11.59
Head and neck squamous cell carcinoma No 11 8 2.13
Breast carcinoma No 11 7 0.61
Stomach adenocarcinoma No 7 6 3.73
Uterine corpus endometrioid carcinoma No 6 5 2.17
Glioblastoma multiforme No 5 5 1.32
Bladder carcinoma No 5 4 4.08
Serous ovarian adenocarcinoma No 5 3 0.95
Renal clear cell carcinoma No 4 2 0.48
Lower grade glioma No 3 2 1.18
Diffuse B cell lymphoma No 2 2 8.70
Hepatocarcinoma No 3 1 1.11
Acute myeloid leukemia No 1 1 0.51
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 2 1 0.31
Non small cell lung carcinoma No 1 1 3.23
Colorectal adenocarcinoma No 1 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence