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MUC7 has not been detected as a mutational cancer driver

MUC7
Ensembl id ENSG00000171195
Mutated samples
Coding Sequence 94 (1.4%)
Protein Affecting 80 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MUC7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 21 5.69
Lung adenocarcinoma No 18 17 4.35
Bladder carcinoma No 5 5 5.10
Thyroid carcinoma No 6 5 1.55
Lower grade glioma No 4 4 2.37
Prostate adenocarcinoma No 4 3 1.23
Breast carcinoma No 4 3 0.26
Uterine corpus endometrioid carcinoma No 4 3 1.30
Colorectal adenocarcinoma No 3 3 1.31
Head and neck squamous cell carcinoma No 4 3 0.80
Lung squamous cell carcinoma No 2 2 1.15
Renal clear cell carcinoma No 2 2 0.48
Serous ovarian adenocarcinoma No 3 2 0.63
Stomach adenocarcinoma No 3 2 1.24
Glioblastoma multiforme No 3 2 0.53
Non small cell lung carcinoma No 1 1 3.23
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 1 1 0.68
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence