Top
MUC4 has not been detected as a mutational cancer driver

MUC4
Ensembl id ENSG00000145113
Mutated samples
Coding Sequence 80 (1.2%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MUC4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 30 16 4.34
Prostate adenocarcinoma No 15 14 5.76
Small cell lung carcinoma No 6 6 8.70
Esophageal carcinoma No 5 4 2.74
Hepatocarcinoma No 3 2 2.22
Breast carcinoma No 4 2 0.17
Pancreas adenocarcinoma No 2 2 0.93
Neuroblastoma No 4 2 0.95
Head and neck squamous cell carcinoma No 2 2 0.53
Medulloblastoma No 2 1 0.48
Stomach adenocarcinoma No 2 1 0.62
Chronic lymphocytic leukemia No 5 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence