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MTR has not been detected as a mutational cancer driver

MTR
Ensembl id ENSG00000116984
Mutated samples
Coding Sequence 89 (1.3%)
Protein Affecting 61 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MTR gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 21 10 2.71
Lung adenocarcinoma No 12 9 2.30
Lung squamous cell carcinoma No 9 7 4.02
Stomach adenocarcinoma No 8 6 3.73
Uterine corpus endometrioid carcinoma No 7 5 2.17
Head and neck squamous cell carcinoma No 5 5 1.33
Bladder carcinoma No 4 4 4.08
Breast carcinoma No 6 4 0.35
Pancreas adenocarcinoma No 2 2 0.93
Thyroid carcinoma No 2 2 0.62
Colorectal adenocarcinoma No 3 2 0.87
Esophageal carcinoma No 2 2 1.37
Hepatocarcinoma No 2 1 1.11
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Medulloblastoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence