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MTF1 has not been detected as a mutational cancer driver

MTF1
Ensembl id ENSG00000188786
Mutated samples
Coding Sequence 54 (0.8%)
Protein Affecting 40 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MTF1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 9 2.44
Breast carcinoma No 3 3 0.26
Renal clear cell carcinoma No 3 3 0.72
Uterine corpus endometrioid carcinoma No 4 3 1.30
Small cell lung carcinoma No 3 3 4.35
Head and neck squamous cell carcinoma No 3 3 0.80
Glioblastoma multiforme No 3 3 0.79
Prostate adenocarcinoma No 2 2 0.82
Lung adenocarcinoma No 3 2 0.51
Bladder carcinoma No 2 2 2.04
Lung squamous cell carcinoma No 4 2 1.15
Stomach adenocarcinoma No 5 2 1.24
Pancreas adenocarcinoma No 1 1 0.47
Serous ovarian adenocarcinoma No 2 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Chronic lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence