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MST1R has not been detected as a mutational cancer driver

MST1R
Ensembl id ENSG00000164078
Mutated samples
Coding Sequence 76 (1.1%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MST1R gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 8 2.17
Stomach adenocarcinoma No 6 6 3.73
Uterine corpus endometrioid carcinoma No 7 5 2.17
Head and neck squamous cell carcinoma No 7 5 1.33
Lung adenocarcinoma No 8 4 1.02
Bladder carcinoma No 5 4 4.08
Renal clear cell carcinoma No 4 4 0.96
Lung squamous cell carcinoma No 3 3 1.72
Serous ovarian adenocarcinoma No 4 3 0.95
Glioblastoma multiforme No 4 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Acute myeloid leukemia No 1 1 0.51
Breast carcinoma No 2 1 0.09
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 1 1 0.48
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 1 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence