MSH6 has not been detected as a mutational cancer driver in this cancer type

Projects 2
210 Samples
Coding sequence mutations (CSMs)
in driver genes 161
in all genes 8146
Protein affecting mutations (PAMs)
in driver genes 159
in all genes 2132
Ensembl id ENSG00000116062
Mutated samples
Coding Sequence 1 (0.5%)
Protein Affecting 1 (0.5%)
Mode of action Unclassified
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Medulloblastoma projects in all MSH6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Pediatric brain tumors DKFZ No 1 1 0.48
The mutations needle plot shows the distribution of the observed MSH6 cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification