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MRPS22 has not been detected as a mutational cancer driver

MRPS22
Ensembl id ENSG00000175110
Mutated samples
Coding Sequence 153 (2.3%)
Protein Affecting 14 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MRPS22 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Bladder carcinoma No 8 4 4.08
Breast carcinoma No 6 2 0.17
Serous ovarian adenocarcinoma No 5 2 0.63
Head and neck squamous cell carcinoma No 8 2 0.53
Renal clear cell carcinoma No 3 1 0.24
Uterine corpus endometrioid carcinoma No 13 1 0.43
Stomach adenocarcinoma No 7 1 0.62
Diffuse B cell lymphoma No 1 1 4.35
Prostate adenocarcinoma No 1 0 0.00
Lung adenocarcinoma No 14 0 0.00
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 11 0 0.00
Cutaneous melanoma No 49 0 0.00
Neuroblastoma No 2 0 0.00
Chronic lymphocytic leukemia No 6 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Small cell lung carcinoma No 3 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 7 0 0.00
Esophageal carcinoma No 5 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence