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MASP2 has not been detected as a mutational cancer driver

MASP2
Ensembl id ENSG00000009724
Mutated samples
Coding Sequence 51 (0.8%)
Protein Affecting 30 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MASP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 9 2.44
Bladder carcinoma No 5 3 3.06
Breast carcinoma No 5 3 0.26
Lung adenocarcinoma No 2 2 0.51
Serous ovarian adenocarcinoma No 3 2 0.63
Head and neck squamous cell carcinoma No 4 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Hepatocarcinoma No 2 1 1.11
Lung squamous cell carcinoma No 1 1 0.57
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 4 1 0.43
Stomach adenocarcinoma No 1 1 0.62
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 2 1 0.68
Medulloblastoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence