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MAP4 has not been detected as a mutational cancer driver

MAP4
Ensembl id ENSG00000047849
Mutated samples
Coding Sequence 121 (1.8%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MAP4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 11 2.98
Breast carcinoma No 10 5 0.44
Uterine corpus endometrioid carcinoma No 9 4 1.74
Lung adenocarcinoma No 8 3 0.77
Bladder carcinoma No 6 3 3.06
Lung squamous cell carcinoma No 3 3 1.72
Stomach adenocarcinoma No 7 3 1.86
Renal clear cell carcinoma No 5 2 0.48
Neuroblastoma No 2 2 0.95
Multiple myeloma No 2 2 2.90
Serous ovarian adenocarcinoma No 5 2 0.63
Head and neck squamous cell carcinoma No 9 2 0.53
Non small cell lung carcinoma No 2 1 3.23
Colorectal adenocarcinoma No 3 1 0.44
Esophageal carcinoma No 3 1 0.68
Prostate adenocarcinoma No 2 0 0.00
Hepatocarcinoma No 4 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 4 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Lower grade glioma No 3 0 0.00
Small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence