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MAP2 has not been detected as a mutational cancer driver

MAP2
Ensembl id ENSG00000078018
Mutated samples
Coding Sequence 179 (2.6%)
Protein Affecting 131 (1.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MAP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 19 16 1.39
Lung adenocarcinoma No 17 15 3.84
Stomach adenocarcinoma No 20 15 9.32
Cutaneous melanoma No 20 14 3.79
Head and neck squamous cell carcinoma No 15 14 3.73
Esophageal carcinoma No 15 12 8.22
Lung squamous cell carcinoma No 12 8 4.60
Colorectal adenocarcinoma No 14 8 3.49
Serous ovarian adenocarcinoma No 11 7 2.22
Small cell lung carcinoma No 6 6 8.70
Uterine corpus endometrioid carcinoma No 6 4 1.74
Bladder carcinoma No 3 3 3.06
Acute myeloid leukemia No 3 2 1.02
Renal clear cell carcinoma No 3 2 0.48
Hepatocarcinoma No 3 1 1.11
Pancreas adenocarcinoma No 2 1 0.47
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 1 1 3.23
Glioblastoma multiforme No 1 1 0.26
Chronic lymphocytic leukemia No 6 0 0.00
Multiple myeloma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence