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MAGI1 has not been detected as a mutational cancer driver

MAGI1
Ensembl id ENSG00000151276
Mutated samples
Coding Sequence 155 (2.3%)
Protein Affecting 96 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all MAGI1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 62 37 10.03
Lung adenocarcinoma No 11 11 2.81
Lung squamous cell carcinoma No 8 7 4.02
Stomach adenocarcinoma No 9 7 4.35
Breast carcinoma No 4 4 0.35
Uterine corpus endometrioid carcinoma No 8 4 1.74
Colorectal adenocarcinoma No 5 4 1.75
Esophageal carcinoma No 7 4 2.74
Bladder carcinoma No 4 3 3.06
Head and neck squamous cell carcinoma No 6 3 0.80
Hepatocarcinoma No 5 2 2.22
Renal clear cell carcinoma No 4 2 0.48
Serous ovarian adenocarcinoma No 2 2 0.63
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 2 2 0.53
Acute myeloid leukemia No 1 1 0.51
Diffuse B cell lymphoma No 1 1 4.35
Prostate adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 11 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence