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LYAR has not been detected as a mutational cancer driver

LYAR
Ensembl id ENSG00000145220
Mutated samples
Coding Sequence 21 (0.3%)
Protein Affecting 16 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LYAR gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 5 4 1.02
Stomach adenocarcinoma No 3 3 1.86
Cutaneous melanoma No 2 2 0.54
Head and neck squamous cell carcinoma No 2 2 0.53
Hepatocarcinoma No 1 1 1.11
Lung squamous cell carcinoma No 1 1 0.57
Renal clear cell carcinoma No 1 1 0.24
Serous ovarian adenocarcinoma No 1 1 0.32
Esophageal carcinoma No 1 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence