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LTBP1 has not been detected as a mutational cancer driver

LTBP1
Ensembl id ENSG00000049323
Mutated samples
Coding Sequence 186 (2.7%)
Protein Affecting 143 (2.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LTBP1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 46 36 9.76
Lung adenocarcinoma No 32 27 6.91
Head and neck squamous cell carcinoma No 17 17 4.53
Lung squamous cell carcinoma No 19 15 8.62
Breast carcinoma No 10 7 0.61
Bladder carcinoma No 7 5 5.10
Stomach adenocarcinoma No 10 5 3.11
Prostate adenocarcinoma No 4 3 1.23
Renal clear cell carcinoma No 5 3 0.72
Serous ovarian adenocarcinoma No 4 3 0.95
Small cell lung carcinoma No 3 3 4.35
Hepatocarcinoma No 3 2 2.22
Pancreas adenocarcinoma No 2 2 0.93
Neuroblastoma No 2 2 0.95
Uterine corpus endometrioid carcinoma No 3 2 0.87
Non small cell lung carcinoma No 3 2 6.45
Colorectal adenocarcinoma No 2 2 0.87
Glioblastoma multiforme No 3 2 0.53
Thyroid carcinoma No 1 1 0.31
Chronic lymphocytic leukemia No 3 1 0.34
Diffuse B cell lymphoma No 1 1 4.35
Esophageal carcinoma No 2 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Pylocytic astrocytoma No 3 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence